Proton Mail Business vs LuxSci

Proton Mail Business

Proton Mail Business provides zero-access end-to-end encrypted email hosted in Switzerland under some of the world's strongest privacy laws. Messages are encrypted on-device before reaching Proton's servers, meaning even Proton cannot read your email. For HIPAA-covered entities, Proton signs BAAs on its Business and Enterprise plans. The platform includes a full suite of privacy tools including Proton Calendar, Drive, and VPN.

Pros
  • Strongest privacy protections. Zero-access encryption
  • Swiss jurisdiction beyond US and EU reach
  • Open source and independently audited
  • Affordable per-user pricing
  • Complete privacy suite (mail, calendar, drive, VPN)
Considerations
  • Non-Proton recipients see messages via secure portal
  • Fewer enterprise admin features than competitors
  • Migration from existing email providers can be complex
  • Limited third-party integrations

Pricing: Free and open source; paid tiers on the vendor site.

LuxSci

LuxSci provides HIPAA-compliant email hosting and encryption as a combined service, eliminating the need for separate email and encryption vendors. It offers multiple encryption methods. TLS, portal pickup, PGP, and S/MIME. With policy-based automation that selects the right method per message. LuxSci signs BAAs and provides dedicated infrastructure for healthcare organizations that need both email hosting and encryption under one HIPAA-compliant umbrella.

Pros
  • Single vendor for email hosting + encryption
  • Flexible encryption methods per recipient
  • Dedicated infrastructure avoids shared-tenant risks
  • Affordable for small and mid-size practices
  • Strong API for automated workflows
Considerations
  • Smaller company with less brand recognition
  • Interface less polished than larger competitors
  • Limited ecosystem integrations beyond email
  • Portal experience for non-TLS recipients

Pricing: See the vendor site for current pricing.